⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398959 | 0.83 | CYP1A2 (0.32) | — | |
| SCHEMBL24463148 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL17378584 | 0.63 | CYP1A2 (0.40) | — | |
| SCHEMBL6950074 | 0.63 | TLR8 (0.44) | — | |
| SCHEMBL15004570 | 0.62 | PDE3B (0.40) | — | |
| SCHEMBL24463121 | 0.62 | ACSS2 (0.39) | — | |
| SCHEMBL10187684 | 0.60 | ACSS2 (0.52) | — | |
| SCHEMBL30038517 | 0.59 | HSD11B1 (0.35) | — | |
| SCHEMBL28331893 | 0.59 | CYP1A2 (0.40) | — | |
| SCHEMBL17417563 | 0.59 | TAAR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176813-A | Tricyclic heterocyclic compound with FGFR inhibition effect, pharmaceutical composition containing tricyclic heterocyclic compound and application of pharmaceutical composition | 上海科恩泰生物医药科技有限公司 | 2024-12-24 | — | — | CN | disclosed |