Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | LITAF | Q99732 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398996 | 0.89 | SRC (0.50) | SRCEGFRABL1ABL2PIK3CA | |
| SCHEMBL31398985 | 0.81 | SRC (0.43) | SRCEGFRABL1ABL2PIK3CA | |
| SCHEMBL31398964 | 0.75 | SRC (0.52) | SRCEGFRABL1ABL2PIK3CA | |
| SCHEMBL9950465 | 0.75 | SRC (0.54) | SRCEGFRABL1ABL2PIK3CA | |
| SCHEMBL515118 | 0.75 | SRC (0.54) | SRCEGFRABL1ABL2PIK3CA | |
| SCHEMBL31399002 | 0.74 | SRC (0.53) | SRCEGFRABL1ABL2PIK3CA | |
| SCHEMBL31398863 | 0.72 | JAK2 (0.39) | PIK3CDUSP30MAPT | |
| SCHEMBL1449722 | 0.71 | TNF (0.46) | SRCEGFRTNFLITAFNR3C1 | |
| SCHEMBL515111 | 0.71 | GPR119 (0.57) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL952015 | 0.71 | TP53 (0.45) | KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176813-A | Tricyclic heterocyclic compound with FGFR inhibition effect, pharmaceutical composition containing tricyclic heterocyclic compound and application of pharmaceutical composition | 上海科恩泰生物医药科技有限公司 | 2024-12-24 | — | — | CN | disclosed |