Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870376 | 0.80 | NR1H2 (0.43) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL16824590 | 0.80 | HSD17B10 (0.42) | SMN1; SMN2KMT2AMEN1ATMLMNA | |
| SCHEMBL16824591 | 0.80 | HSD17B10 (0.42) | SMN1; SMN2KMT2AMEN1ATMLMNA | |
| SCHEMBL610128 | 0.80 | HSD17B10 (0.42) | SMN1; SMN2KMT2AMEN1ATMLMNA | |
| SCHEMBL28621971 | 0.75 | LMNA (0.47) | ALDH1A1KMT2AMEN1LMNANPSR1 | |
| SCHEMBL28202604 | 0.75 | CHRM2 (0.42) | SMN1; SMN2LMNANPSR1POLBCYP1A2 | |
| SCHEMBL617770 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL12072337 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL13990630 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL13359249 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |