SCHEMBL31399703

SCHEMBL31399703

COc1ncc(F)c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
MAPT P10636 3/20 0.40
CASP1 P29466 1/20 0.40
ESR1 P03372 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
PIK3CA P42336 2/20 0.38
KMT2A Q03164 1/20 0.36
POLB P06746 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SYK P43405 2/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23795318 1.00 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C19MAPTCASP1
SCHEMBL8271649 0.78 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C19MAPTCASP1
SCHEMBL8271643 0.78 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C19MAPTCASP1
SCHEMBL8272299 0.77 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C19MAPTESR1
SCHEMBL1239659 0.76 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C19MAPTCASP1
SCHEMBL8272616 0.76 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C19MAPTCASP1
SCHEMBL999151 0.76 ALDH1A1 (0.33) ALDH1A1CYP1A2CYP2C19ESR1SYK
SCHEMBL22094077 0.76 ALDH1A1 (0.48) ALDH1A1CYP1A2CYP2C19MAPTCASP1
SCHEMBL21872083 0.74 ALDH1A1 (0.52) ALDH1A1CYP1A2CYP2C19MAPTCASP1
SCHEMBL22094445 0.73 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C19MAPTCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739672-A1 NEW COMPOUNDS Aston University (GB) 2026-05-13 EP disclosed
WO-2025008626-A1 NEW COMPOUNDS ASTON UNIVERSITY (GB) 2025-01-09 WO disclosed