SCHEMBL31400263

SCHEMBL31400263

COc1ccc(-c2cc(-c3ccccn3)cc(-c3ccccn3)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
HSP90AA1 P07900 1/20 0.56
PKM P14618 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CLK4 Q9HAZ1 1/20 0.55
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP19A1 P11511 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
KDR P35968 1/20 0.52
ABL1 P00519 1/20 0.51
ABCB1 P08183 1/20 0.51
BCR P11274 1/20 0.51
TGFBR1 P36897 3/20 0.51
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
THRB P10828 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21988541 1.00 NPC1 (0.56) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL13458064 0.91 CYP19A1 (0.62) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL28428427 0.90 ABL1 (0.57) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL29496947 0.89 CYP19A1 (0.64) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL913393 0.89 CYP19A1 (0.64) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL8248415 0.87 NPC1 (0.52) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL31260432 0.87 NPC1 (0.57) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL7454751 0.87 NPC1 (0.57) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL28208710 0.84 CYP1A2 (0.56) NPC1RAB9AHSP90AA1PKML3MBTL1
SCHEMBL22142572 0.83 TGFBR1 (0.59) NPC1RAB9AHSP90AA1PKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775323-A Transition metal luminescent complexes and methods of use 香港大学 2025-04-08 CN disclosed
CN-111269711-B Transition metal luminescent complexes and methods of use 香港大学 2025-02-25 CN disclosed