Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 2/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926107 | 0.84 | LCK (0.41) | LCKFYNMRGPRX4CYP1A2ALOX15 | |
| SCHEMBL29639684 | 0.84 | LCK (0.41) | LCKFYNMRGPRX4CYP1A2ALOX15 | |
| SCHEMBL24017473 | 0.83 | LCK (0.52) | LCKFYNCYP1A2ALOX15SMN1; SMN2 | |
| SCHEMBL29728986 | 0.82 | WDR5 (0.43) | LCKFYNMRGPRX4CYP1A2TSHR | |
| SCHEMBL23213468 | 0.82 | WDR5 (0.43) | LCKFYNMRGPRX4CYP1A2TSHR | |
| SCHEMBL27893362 | 0.81 | MRGPRX4 (0.47) | LCKFYNMRGPRX4ALOX15GFER | |
| SCHEMBL4235825 | 0.81 | MRGPRX4 (0.47) | MRGPRX4ALOX15GFERADAM17SMN1; SMN2 | |
| SCHEMBL23464784 | 0.80 | AKR1C3 (0.39) | LCKFYNMRGPRX4CYP1A2LMNA | |
| SCHEMBL31401023 | 0.77 | HCAR1 (0.48) | LCKFYNCYP1A2LMNAALDH1A1 | |
| SCHEMBL24017267 | 0.76 | LCK (0.44) | LCKFYNCYP1A2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739682-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | Janssen Pharmaceutica NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008058-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-09 | — | — | WO | disclosed |