Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | PTPRB | P23467 | 1/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902549 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL1030801 | 0.95 | SNCA (0.51) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL31255683 | 0.88 | CASP6 (0.58) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL429785 | 0.88 | CASP6 (0.58) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL11155537 | 0.86 | CASP6 (0.56) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL10864839 | 0.86 | CASP6 (0.56) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL2290226 | 0.86 | CASP6 (0.56) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL5346617 | 0.86 | CASP6 (0.56) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL479266 | 0.86 | ALDH1A1 (0.54) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 | |
| SCHEMBL29370096 | 0.86 | ALDH1A1 (0.54) | CYP1A2CYP2C9HIF1ACYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119789853-A | Dexmedetomidine for the treatment of sleep disorders | 苏黎世大学 | 2025-04-08 | — | — | CN | disclosed |