Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402198 | 0.86 | F10 (0.57) | NR1H4F10PPARGPPARAHDAC1 | |
| SCHEMBL31635248 | 0.82 | HDAC1 (0.55) | NR1H4F10PPARDPPARGPPARA | |
| SCHEMBL6120276 | 0.72 | CA12 (0.54) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1435144 | 0.71 | HDAC1 (0.54) | F10HDAC1HDAC3HDAC6MEN1 | |
| SCHEMBL2411168 | 0.71 | NR1H4 (0.55) | NR1H4F10PPARDPPARGPPARA | |
| SCHEMBL3821744 | 0.70 | F10 (0.93) | F10HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL1064323 | 0.69 | HDAC1 (0.53) | NR1H4F10HDAC1MEN1KMT2A | |
| SCHEMBL30944730 | 0.69 | HDAC1 (0.53) | NR1H4F10HDAC1MEN1KMT2A | |
| SCHEMBL2732298 | 0.69 | HDAC1 (0.53) | NR1H4F10PPARAHDAC1HDAC3 | |
| SCHEMBL6671456 | 0.69 | SMN1; SMN2 (0.57) | KMT2AALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306700-A | DNMT1-HDAC double-target inhibitor and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | disclosed |