Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686588 | 0.86 | GAA (0.60) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL7523030 | 0.80 | HCAR2 (0.49) | CA12CA2CA9HCAR2KMT2A | |
| SCHEMBL31402198 | 0.80 | F10 (0.57) | CA2L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL4749159 | 0.79 | DHODH (0.69) | CA12CA2CA9CFDKMT2A | |
| SCHEMBL6671456 | 0.78 | SMN1; SMN2 (0.57) | CA12CA2CA9L3MBTL1KMT2A | |
| SCHEMBL222446 | 0.78 | RXFP1 (0.55) | CA12CA2CA9HCAR2KMT2A | |
| SCHEMBL29702265 | 0.78 | RXFP1 (0.55) | CA12CA2CA9HCAR2KMT2A | |
| SCHEMBL8686791 | 0.76 | ALDH1A1 (0.70) | CA12CA2CA9CFDKMT2A | |
| SCHEMBL1463287 | 0.76 | GRIK1 (0.72) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1462398 | 0.76 | MEN1 (0.77) | HCAR2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2642994-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | Ligand Pharmaceuticals Incorporated (US) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |