Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402215 | 0.86 | NR1H4 (0.52) | F10KMT2AMEN1HDAC1HDAC3 | |
| SCHEMBL3662421 | 0.80 | F10 (0.53) | F10KMT2AMEN1HDAC1L3MBTL1 | |
| SCHEMBL6120276 | 0.80 | CA12 (0.54) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL6119612 | 0.78 | SRD5A2 (0.48) | KMT2AMEN1NR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL19501531 | 0.76 | SIRT1 (0.64) | KMT2AMEN1HDAC1HDAC3HDAC2 | |
| SCHEMBL16583906 | 0.75 | RAB9A (0.70) | F10KMT2AMEN1HDAC1HDAC8 | |
| SCHEMBL3821744 | 0.74 | F10 (0.93) | F10KMT2AMEN1HDAC1HDAC3 | |
| SCHEMBL6671456 | 0.74 | SMN1; SMN2 (0.57) | KMT2AL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL21051097 | 0.73 | POLB (0.55) | KMT2AHDAC1HDAC3HDAC2HDAC7 | |
| SCHEMBL19500918 | 0.73 | F10 (0.77) | F10KMT2AMEN1HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306700-A | DNMT1-HDAC double-target inhibitor and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | disclosed |