Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 8/20 | 0.75 |
| ▸ | DRD2 | P14416 | 2/20 | 0.75 |
| ▸ | DRD3 | P35462 | 2/20 | 0.75 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330686 | 1.00 | PNMT (0.75) | PNMTDRD2DRD3CHRNA1CHRNG | |
| Hydrochloric Acid SCHEMBL21800263 | 0.98 | PNMT (0.72) | PNMTDRD2DRD3CHRNA1CHRNG | |
| SCHEMBL351435 | 0.86 | PNMT (1.00) | PNMTDRD2DRD3ADRA2AADRA2B | |
| SCHEMBL29365632 | 0.86 | PNMT (1.00) | PNMTDRD2DRD3ADRA2AADRA2B | |
| SCHEMBL1638541 | 0.86 | DRD2 (1.00) | PNMTDRD2DRD3ADRA2AADRA2B | |
| SCHEMBL29580085 | 0.86 | DRD2 (1.00) | PNMTDRD2DRD3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL30015379 | 0.84 | DRD2 (0.96) | PNMTDRD2DRD3ADRA2AADRA2B | |
| SCHEMBL20374032 | 0.84 | PNMT (0.56) | PNMTDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4224148 | 0.84 | DRD2 (0.96) | PNMTDRD2DRD3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL65520 | 0.84 | PNMT (0.96) | PNMTDRD2DRD3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021182-A1 | CYP11A1 INHIBITORS | ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) | 2025-01-30 | — | — | WO | disclosed |