SCHEMBL31403166

SCHEMBL31403166

[2H]C([2H])([2H])Oc1cncc(B(O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.39
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MKNK2 Q9HBH9 2/20 0.31
MKNK1 Q9BUB5 1/20 0.31
ROCK2 O75116 1/20 0.31
MAP4K4 O95819 1/20 0.31
PRKACA P17612 1/20 0.31
ROCK1 Q13464 1/20 0.31
DYRK1A Q13627 1/20 0.31
NTRK3 Q16288 1/20 0.31
PKN2 Q16513 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
STK17A Q9UEE5 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4958 0.86 ENPP2 (0.52) ENPP2CA1CA2MKNK2MKNK1
Water SCHEMBL2422179 0.85 ENPP2 (0.50) ENPP2CA1CA2MKNK2MKNK1
SCHEMBL29952177 0.78 ENPP2 (0.45) ENPP2CA1CA2TUBB4ATUBB
SCHEMBL29955628 0.74 CYP11B1 (0.42) ENPP2CYP11B1CYP11B2
SCHEMBL2083713 0.74 CHRNB2 (0.40) ENPP2CA1CA2CYP3A4CYP11B1
SCHEMBL2214024 0.74 CYP11B1 (0.42) ENPP2CYP11B1CYP11B2
SCHEMBL15664521 0.72
SCHEMBL28967087 0.72 ENPP2 (0.36) ENPP2CA1CA2
SCHEMBL13651756 0.72 GGPS1 (0.38) MKNK2ROCK2MAP4K4PRKACAROCK1
SCHEMBL30693949 0.72 ENPP2 (0.75) ENPP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021182-A1 CYP11A1 INHIBITORS ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) 2025-01-30 WO disclosed