Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 6/20 | 0.63 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | ULK1 | O75385 | 12/20 | 0.54 |
| ▸ | ULK2 | Q8IYT8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403274 | 1.00 | CHEK1 (0.63) | CHEK1FLT3ULK1ULK2 | |
| SCHEMBL31403199 | 0.90 | CHEK1 (0.56) | CHEK1FLT3 | |
| SCHEMBL31403276 | 0.80 | TYRO3 (0.62) | CHEK1FLT3 | |
| SCHEMBL17545176 | 0.75 | ULK1 (0.88) | FLT3ULK1ULK2 | |
| SCHEMBL31666635 | 0.75 | CCNK (0.61) | CHEK1FLT3ULK1 | |
| SCHEMBL31666582 | 0.75 | CCNK (0.61) | CHEK1FLT3ULK1 | |
| SCHEMBL30260876 | 0.73 | CHEK1 (0.58) | CHEK1FLT3ULK1ULK2 | |
| SCHEMBL17545009 | 0.72 | ULK1 (0.70) | ULK1ULK2 | |
| SCHEMBL30260956 | 0.72 | CCNK (0.57) | CHEK1FLT3ULK1 | |
| SCHEMBL30261007 | 0.72 | ULK1 (0.65) | CHEK1FLT3ULK1ULK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462522-A | N2-3-Fluoro-5-substituted phenyl-2-aminopyrimidine derivative, preparation method and medical application thereof | 浙江大学 | 2025-02-18 | — | — | CN | disclosed |