SCHEMBL31403680

SCHEMBL31403680

O=C1CCC(N2Cc3cc(C(=O)Nc4nccc(OCCO)n4)ccc3C2=O)C(=O)N1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 10/20 0.54
▸ CSNK1A1 P48729 2/20 0.54
▸ IKZF2 Q9UKS7 9/20 0.44
▸ GSPT1 P15170 1/20 0.44
▸ DDB1 Q16531 1/20 0.44
▸ IKZF3 Q9UKT9 1/20 0.44
▸ HDAC3 O15379 1/20 0.43
▸ HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31403758 0.88 CRBN (0.49) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31403590 0.88 CRBN (0.54) CRBNCSNK1A1IKZF2
SCHEMBL31403539 0.85 CRBN (0.51) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31403614 0.82 CRBN (0.55) CRBNCSNK1A1IKZF2
SCHEMBL31403715 0.80 CRBN (0.47) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31159156 0.78 CRBN (0.62) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31158945 0.76 CRBN (0.82) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31158788 0.76 CRBN (0.60) CRBNCSNK1A1IKZF2HDAC3HDAC1
SCHEMBL22713505 0.75 CRBN (0.63) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31289139 0.75 CRBN (0.65) CRBNCSNK1A1IKZF2GSPT1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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