SCHEMBL31403715

SCHEMBL31403715

CC(C)(C)OC(=O)N1CCC(Oc2ccnc(NC(=O)c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)n2)C1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.47
▸ CSNK1A1 P48729 3/20 0.47
▸ GRAMD1A Q96CP6 6/20 0.41
▸ IKZF2 Q9UKS7 6/20 0.40
▸ DDB1 Q16531 4/20 0.40
▸ GSPT1 P15170 1/20 0.39
▸ IKZF3 Q9UKT9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31403590 0.85 CRBN (0.54) CRBNCSNK1A1IKZF2
SCHEMBL31403539 0.83 CRBN (0.51) CRBNCSNK1A1IKZF2DDB1GSPT1
SCHEMBL20234476 0.81 IKZF2 (0.47) CRBNCSNK1A1IKZF2DDB1GSPT1
SCHEMBL32669075 0.81 CRBN (0.52) CRBNCSNK1A1IKZF2DDB1
SCHEMBL31413474 0.81 CRBN (0.52) CRBNCSNK1A1IKZF2DDB1
SCHEMBL31403680 0.80 CRBN (0.54) CRBNCSNK1A1IKZF2DDB1GSPT1
SCHEMBL31403758 0.79 CRBN (0.49) CRBNCSNK1A1IKZF2DDB1GSPT1
SCHEMBL30341676 0.77 CRBN (0.64) CRBNCSNK1A1IKZF2DDB1GSPT1
SCHEMBL29126557 0.77 CRBN (0.64) CRBNCSNK1A1IKZF2DDB1GSPT1
SCHEMBL20046226 0.76 CRBN (0.54) CRBNCSNK1A1IKZF2DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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