SCHEMBL31403539

SCHEMBL31403539

O=C1CCC(N2Cc3cc(C(=O)Nc4nccc(OC5CCNC5)n4)ccc3C2=O)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 16/20 0.51
▸ CSNK1A1 P48729 9/20 0.51
▸ IKZF2 Q9UKS7 11/20 0.42
▸ GSPT1 P15170 1/20 0.40
▸ DDB1 Q16531 1/20 0.40
▸ IKZF3 Q9UKT9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31403590 0.91 CRBN (0.54) CRBNCSNK1A1IKZF2
SCHEMBL31403680 0.85 CRBN (0.54) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31403715 0.83 CRBN (0.47) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31403758 0.80 CRBN (0.49) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31403614 0.79 CRBN (0.55) CRBNCSNK1A1IKZF2
SCHEMBL31403491 0.78 CRBN (0.54) CRBNIKZF2DDB1IKZF3
SCHEMBL31403650 0.77 CRBN (0.56) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL20234479 0.76 CRBN (0.52) CRBNCSNK1A1IKZF2
SCHEMBL23350211 0.76 CRBN (0.63) CRBNCSNK1A1IKZF2
SCHEMBL20231670 0.76 CRBN (0.63) CRBNCSNK1A1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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