Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140459 | 1.00 | NFE2L2 (0.61) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL29089429 | 1.00 | NFE2L2 (0.61) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL11115893 | 0.98 | NFE2L2 (0.59) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL11115897 | 0.98 | NFE2L2 (0.59) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL29089413 | 0.92 | NFE2L2 (0.53) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL29089423 | 0.90 | NFE2L2 (0.52) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL29089427 | 0.89 | POLB (0.55) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL29089411 | 0.89 | MAPT (0.51) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL29089415 | 0.89 | MAPT (0.51) | NFE2L2HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL29089436 | 0.89 | CYP1B1 (0.53) | NFE2L2HDAC1HDAC2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075431-A1 | FORMALDEHYDE DETECTOR BODY, FORMALDEHYDE DETECTOR, FORMALDEHYDE DETECTION METHOD AND FORMALDEHYDE DETECTION REAGENT | DAIKIN INDUSTRIES, LTD. (JP) | 2010-03-25 | — | — | US | claimed |
| EP-2085769-A1 | FORMALDEHYDE DETECTING MATERIAL, FORMALDEHYDE DETECTOR, FORMALDEHYDE DETECTING METHOD AND FORMALDEHYDE DETECTING REAGENT | Daikin Industries, Ltd. (JP) | 2009-08-05 | — | — | EP | claimed |
| CN-116496201-A | Preparation method of aza spirocyclic ketone compound and dihydroxyl hydroindole compound | 昆明理工大学 | 2023-07-28 | — | — | CN | disclosed |
| US-20100075431-A1 | FORMALDEHYDE DETECTOR BODY, FORMALDEHYDE DETECTOR, FORMALDEHYDE DETECTION METHOD AND FORMALDEHYDE DETECTION REAGENT | DAIKIN INDUSTRIES, LTD. (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2085769-A1 | FORMALDEHYDE DETECTING MATERIAL, FORMALDEHYDE DETECTOR, FORMALDEHYDE DETECTING METHOD AND FORMALDEHYDE DETECTING REAGENT | Daikin Industries, Ltd. (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-4565824-A | Certain nitratoalkyl ester dihydropyridines having antihypertensive properties | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-21 | — | — | US | disclosed |
| US-4551467-A | Vasodilating cyanoalkyl esters of 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |
| EP-0110259-A1 | 1,4-Dihydropyridines, processes for their preparation and their use in medicines | BAYER AG (DE) | 1984-06-13 | — | — | EP | disclosed |
| US-4248873-A | Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |
| EP-0012180-A1 | 1,4-Dihydropyridine compounds, their preparation, pharmaceutical compositions containing said compounds and preparation of these compositions | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| EP-0002208-A1 | Nitro 1,4-dihydropyridines, medicaments containing them and their manufacture | BAYER AG (DE) | 1979-06-13 | — | — | EP | disclosed |
| EP-0001769-A1 | Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |