Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788176 | 0.83 | LMNA (0.44) | LMNAXBP1XDH | |
| SCHEMBL15224509 | 0.82 | LMNA (0.36) | LMNAXBP1 | |
| SCHEMBL18788165 | 0.81 | LMNA (0.38) | LMNAXBP1 | |
| SCHEMBL18051022 | 0.80 | HTT (0.41) | LMNAXBP1XDH | |
| SCHEMBL23508158 | 0.68 | MAPK1 (0.30) | — | |
| SCHEMBL17926551 | 0.68 | LMNA (0.40) | LMNAXDHPKM | |
| SCHEMBL23508420 | 0.66 | PDE10A (0.33) | — | |
| SCHEMBL23508176 | 0.65 | SRC (0.30) | — | |
| SCHEMBL16466339 | 0.64 | KDM6B (0.56) | LMNAXDH | |
| SCHEMBL23529884 | 0.64 | XDH (0.36) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025045761-A1 | MOLECULAR GLUE DEGRADERS AND USES THEREOF | MABLINK BIOSCIENCE (FR) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025045758-A1 | ANTIBODY-DRUG CONJUGATES BASED ON MOLECULAR GLUE DEGRADERS AND USES THEREOF | MABLINK BIOSCIENCE (FR) | 2025-03-06 | — | — | WO | disclosed |
| EP-4512806-A1 | MOLECULAR GLUE DEGRADERS AND USES THEREOF | Mablink Bioscience (FR) | 2025-02-26 | — | — | EP | disclosed |
| EP-4512427-A1 | ANTIBODY-DRUG CONJUGATES BASED ON MOLECULAR GLUE DEGRADERS AND USES THEREOF | Mablink Bioscience (FR) | 2025-02-26 | — | — | EP | disclosed |