⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405066 | 0.89 | S1PR4 (0.32) | — | |
| SCHEMBL31405016 | 0.86 | IL1B (0.40) | — | |
| SCHEMBL30375524 | 0.79 | ADORA3 (0.30) | — | |
| SCHEMBL26092878 | 0.79 | ADORA3 (0.30) | — | |
| SCHEMBL31404965 | 0.78 | MRGPRX4 (0.42) | — | |
| SCHEMBL26090020 | 0.77 | HSP90AA1 (0.32) | — | |
| SCHEMBL31405103 | 0.75 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL31405043 | 0.75 | — | — | |
| SCHEMBL31405061 | 0.74 | IL1B (0.45) | — | |
| SCHEMBL31405017 | 0.73 | IL1B (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115558-A1 | PYRIDAZINE DERIVATIVES AND RELATED USES | NODTHERA LTD (GB) | 2025-04-10 | — | — | US | disclosed |