Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31296605 | 0.82 | KDM4E (0.34) | ALDH1A1KMT2AKDM4EPKMHTT | |
| SCHEMBL31405145 | 0.80 | ALDH1A1 (0.34) | PPARAALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL26998248 | 0.77 | FGFR1 (0.42) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL26999128 | 0.76 | MCL1 (0.37) | IRAK4PPARAROCK2ROCK1 | |
| SCHEMBL25423523 | 0.75 | IRAK4 (0.40) | IRAK4PPARAROCK2ROCK1 | |
| SCHEMBL25424986 | 0.74 | AKT2 (0.39) | IRAK4GRM2CLK1CLK2HIPK1 | |
| SCHEMBL26725208 | 0.72 | ACACB (0.39) | ACACBACACAIRAK4ROCK2ROCK1 | |
| SCHEMBL31405130 | 0.72 | KDM4E (0.40) | PPARAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL26998239 | 0.71 | IRAK4 (0.39) | IRAK4PPARAROCK2ROCK1DYRK1A | |
| SCHEMBL26998240 | 0.71 | IRAK4 (0.39) | IRAK4PPARAROCK2ROCK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115579-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2025-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115579-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | CGAS, GLS2, GLS | ACACB 3291/4885ACACA 3213/4885FGFR1 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.