Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901643 | 0.90 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3135519 | 0.83 | EGLN3 (0.54) | KDM4ETP53ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3136508 | 0.82 | EGLN3 (0.65) | KDM4ETP53ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3130203 | 0.80 | EGLN3 (0.55) | KDM4ETP53ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2914566 | 0.78 | KMT2A (0.49) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13037502 | 0.77 | ALDH1A1 (0.48) | KDM4ETP53ALDH1A1GAAKMT2A | |
| SCHEMBL5009323 | 0.76 | KDM4E (0.56) | KDM4ETP53ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2913829 | 0.76 | KMT2A (0.57) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2911429 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1KMT2AMEN1EGLN3 | |
| SCHEMBL2900423 | 0.75 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059549-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |