Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817308 | 0.77 | SLC18A2 (0.62) | HRH3SIGMAR1KCNH2 | |
| SCHEMBL31406212 | 0.76 | HRH3 (0.51) | HRH3KCNH2TAAR1 | |
| SCHEMBL3781357 | 0.74 | SIGMAR1 (0.51) | SIGMAR1KCNH2 | |
| SCHEMBL3781355 | 0.74 | SIGMAR1 (0.51) | SIGMAR1KCNH2 | |
| SCHEMBL17828187 | 0.73 | SIGMAR1 (0.77) | HRH3SIGMAR1KCNH2 | |
| SCHEMBL31406184 | 0.72 | HRH3 (0.57) | HRH3SIGMAR1 | |
| SCHEMBL28858018 | 0.72 | TAAR1 (0.75) | HRH3SIGMAR1KCNH2TAAR1 | |
| SCHEMBL4817496 | 0.71 | HRH3 (0.49) | HRH3TAAR1 | |
| SCHEMBL16056564 | 0.71 | KCNH2 (0.78) | HRH3SIGMAR1KCNH2 | |
| SCHEMBL31406198 | 0.71 | HRH3 (0.61) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025014719-A2 | TROPANE COMPOUNDS FOR TREATING BRAIN DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-16 | — | — | WO | disclosed |