SCHEMBL31406253

SCHEMBL31406253

OCCn1ncc2ccc(Cl)nc21

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMO O15229 10/20 0.37
FSCN1 Q16658 1/20 0.36
HTR2A P28223 3/20 0.34
HTR2C P28335 3/20 0.34
HTR2B P41595 2/20 0.34
CYP1A2 P05177 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MET P08581 1/20 0.33
KMT2A Q03164 1/20 0.32
ABL1 P00519 1/20 0.32
BCR P11274 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31406239 0.83 PDE1A (0.38) KMOHTR2AHTR2CHTR2BABL1
SCHEMBL31469627 0.83 HTR2A (0.34) KMOHTR2AHTR2CHTR2BRECQL
SCHEMBL31469642 0.80 KMO (0.37) KMOHTR2AHTR2CHTR2B
SCHEMBL31469672 0.79 HTR2A (0.38) KMOHTR2AHTR2CHTR2BKMT2A
SCHEMBL31018567 0.79 HTR2A (0.33) KMOHTR2AHTR2CHTR2B
SCHEMBL31018657 0.79 CNR2 (0.36) KMOHTR2AHTR2C
SCHEMBL17682603 0.79 GAA (0.38) KMOHTR2AHTR2CHTR2BKMT2A
SCHEMBL31469691 0.79 GAA (0.38) KMOHTR2AHTR2CHTR2BKMT2A
SCHEMBL23639069 0.77 KMO (0.57) KMOSMN1; SMN2
SCHEMBL24265692 0.75 RECQL (0.56) SMN1; SMN2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119562952-A KIF18A inhibitors 山东轩竹医药科技有限公司 2025-03-04 CN disclosed