Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 3/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682603 | 0.86 | GAA (0.38) | HTR2AHTR2CPOLBKMOCYP11B2 | |
| SCHEMBL31469691 | 0.86 | GAA (0.38) | HTR2AHTR2CPOLBKMOCYP11B2 | |
| SCHEMBL31406253 | 0.83 | KMO (0.37) | HTR2AHTR2CKMOHTR2BABL1 | |
| SCHEMBL31406228 | 0.83 | ADORA3 (0.39) | PDE1APDE1BPDE1CHTR2AHTR2C | |
| SCHEMBL31469627 | 0.83 | HTR2A (0.34) | HTR2AHTR2CRAB9AKMOHTR2B | |
| SCHEMBL31469672 | 0.82 | HTR2A (0.38) | HTR2AHTR2CALDH1A1KMOHTR2B | |
| SCHEMBL31469642 | 0.80 | KMO (0.37) | HTR2AHTR2CKMOHTR2B | |
| SCHEMBL31018567 | 0.79 | HTR2A (0.33) | HTR2AHTR2CKMOHTR2B | |
| SCHEMBL31018657 | 0.79 | CNR2 (0.36) | HTR2AHTR2CKMO | |
| SCHEMBL31469669 | 0.78 | HTR2A (0.43) | HTR2AHTR2CKMOHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562952-A | KIF18A inhibitors | 山东轩竹医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |