Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622757 | 0.93 | ALDH1A1 (0.39) | ALDH1A1CASP1KMT2AMAPK1TSHR | |
| SCHEMBL3410340 | 0.77 | CCR3 (0.43) | CASP1KMT2ACYP3A4MAPTLMNA | |
| SCHEMBL10620013 | 0.76 | KMT2A (0.43) | ALDH1A1CASP1KMT2AMAPK1TSHR | |
| SCHEMBL2232910 | 0.74 | ALDH1A1 (0.56) | ALDH1A1CASP1KMT2AMAPK1TSHR | |
| SCHEMBL1641579 | 0.74 | GBA1 (0.42) | ALDH1A1PDE10A | |
| SCHEMBL12766912 | 0.74 | GBA1 (0.42) | ALDH1A1PDE10A | |
| SCHEMBL4283790 | 0.73 | KMT2A (0.50) | ALDH1A1CASP1KMT2AMAPK1TSHR | |
| SCHEMBL31203132 | 0.73 | HTR1D (0.43) | ALDH1A1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL455280 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CASP1KMT2AMAPK1TSHR | |
| SCHEMBL5953121 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CASP1KMT2AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054369-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |