Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | RAF1 | P04049 | 2/20 | 0.52 |
| ▸ | RET | P07949 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 5/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 5/20 | 0.48 |
| ▸ | MAP3K20 | Q9NYL2 | 4/20 | 0.48 |
| ▸ | FES | P07332 | 2/20 | 0.48 |
| ▸ | FER | P16591 | 2/20 | 0.48 |
| ▸ | HCK | P08631 | 2/20 | 0.48 |
| ▸ | NR2C2 | P49116 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24399682 | 0.84 | BRAF (0.43) | HTTMAPK1ATMRAF1KDR | |
| SCHEMBL30559436 | 0.84 | BRAF (0.43) | HTTMAPK1ATMRAF1KDR | |
| SCHEMBL15066469 | 0.78 | RAF1 (0.66) | HTTMAPK1ATMRAF1MAPK14 | |
| SCHEMBL24268077 | 0.77 | RAPGEF4 (0.49) | RAF1MAPK14KDRBRAF | |
| SCHEMBL15067380 | 0.75 | RAF1 (0.55) | HTTMAPK1ATMRAF1RET | |
| SCHEMBL21387832 | 0.74 | RAF1 (0.63) | HTTMAPK1ATMRAF1MAPK14 | |
| SCHEMBL15066398 | 0.73 | RAF1 (0.53) | HTTMAPK1ATMRAF1MAPK14 | |
| SCHEMBL15066728 | 0.73 | NR1H2 (0.46) | HTTMAPK1ATMRAF1RET | |
| SCHEMBL24399710 | 0.72 | FAAH (0.43) | KDRBRAF | |
| SCHEMBL29638708 | 0.72 | FAAH (0.43) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617213-B1 | THIENO[3,2-D]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES | HANMI PHARMACEUTICAL CO LTD (KR) | 2025-02-19 | — | — | EP | disclosed |