Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698995 | 1.00 | LMNA (0.59) | LMNAMAPK1ACP3BLMNPSR1 | |
| SCHEMBL698996 | 1.00 | LMNA (0.59) | LMNAMAPK1ACP3BLMNPSR1 | |
| SCHEMBL2164471 | 1.00 | LMNA (0.59) | LMNAMAPK1ACP3BLMNPSR1 | |
| SCHEMBL276569 | 0.85 | LMNA (0.73) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL6794371 | 0.82 | PARP1 (0.50) | LMNAACP3PARP1ACHE | |
| SCHEMBL11587930 | 0.82 | CES2 (0.67) | LMNAACP3PARP1SMN1; SMN2 | |
| SCHEMBL28195432 | 0.82 | SRC (0.58) | LMNAACP3NPSR1PARP1ACHE | |
| SCHEMBL4619753 | 0.82 | ACP3 (0.53) | LMNAACP3NPSR1PARP1ACHE | |
| SCHEMBL27937165 | 0.81 | LMNA (0.51) | LMNAMAPK1ACP3PARP1ACHE | |
| SCHEMBL25515020 | 0.81 | ACP3 (0.49) | LMNAMAPK1ACP3EPHX1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | disclosed |