Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410865 | 0.87 | TAS2R14 (0.47) | ALDH1A1CTNNB1WNT3AHSD11B1HPGD | |
| SCHEMBL3302698 | 0.87 | TAS2R14 (0.47) | ALDH1A1CTNNB1WNT3AHSD11B1HPGD | |
| SCHEMBL2024463 | 0.84 | NR4A2 (0.47) | ALDH1A1HPGDKDM4ETAS2R14SMN1; SMN2 | |
| SCHEMBL29575721 | 0.84 | NR4A2 (0.47) | ALDH1A1HPGDKDM4ETAS2R14SMN1; SMN2 | |
| SCHEMBL16549389 | 0.82 | KDM4E (0.56) | ALDH1A1KDM4E | |
| SCHEMBL29760700 | 0.80 | PARP1 (0.50) | PARP1SCN9ACCNCCDK8HASPIN | |
| SCHEMBL30889359 | 0.79 | KDM4E (0.45) | ALDH1A1CTNNB1WNT3AKDM4E | |
| SCHEMBL23275797 | 0.78 | KDM4E (0.44) | ALDH1A1ATMKDM4ESMN1; SMN2 | |
| SCHEMBL29410845 | 0.78 | KDM4E (0.44) | ALDH1A1ATMKDM4ESMN1; SMN2 | |
| SCHEMBL6173688 | 0.77 | PARP1 (0.53) | PARP1SCN9AALDH1A1HSD11B1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011630-A1 | METHOD FOR PREPARING PYRROLE AMIDE COMPOUND AND INTERMEDIATE OF PYRROLE AMIDE COMPOUND | 广东东阳光药业股份有限公司 | 2025-01-16 | — | — | WO | disclosed |
| WO-2025011628-A1 | METHOD FOR PREPARING PYRROLE AMIDE COMPOUND AND INTERMEDIATE THEREOF | 广东东阳光药业股份有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-119306646-A | Process for preparing pyrrole amide compounds and intermediates therefor | 广东东阳光药业股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119306645-A | Process for preparing pyrrole amide compounds and intermediates therefor | 广东东阳光药业股份有限公司 | 2025-01-14 | — | — | CN | disclosed |