Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 4/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | HTR1D | P28221 | 4/20 | 0.34 |
| ▸ | HTR1B | P28222 | 4/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946952 | 0.76 | HTR1A (0.49) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL20399916 | 0.73 | ADORA2A (0.32) | CA1CA2 | |
| SCHEMBL965266 | 0.72 | CSNK2A1 (0.50) | CSNK2A1GPR84AHRNR4A2CMA1 | |
| SCHEMBL8500197 | 0.70 | EPAS1 (0.40) | ALDH1A1 | |
| SCHEMBL1411551 | 0.70 | PTGS1 (0.46) | HPGD | |
| SCHEMBL23709713 | 0.70 | RHEB (0.49) | CSNK2A1GPR84AHRNR4A2CMA1 | |
| SCHEMBL27825202 | 0.69 | EPAS1 (0.43) | ALDH1A1 | |
| SCHEMBL933005 | 0.69 | TRPA1 (0.46) | AHRSCN9AHTR1AHTR1DHTR1B | |
| SCHEMBL30073735 | 0.69 | TRPA1 (0.46) | AHRSCN9AHTR1AHTR1DHTR1B | |
| SCHEMBL2633274 | 0.69 | BCHE (0.46) | AHRHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |