Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31171461 | 1.00 | LMNA (0.42) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31152295 | 1.00 | LMNA (0.42) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31340166 | 1.00 | LMNA (0.42) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31382615 | 0.84 | LMNA (0.38) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31152304 | 0.84 | LMNA (0.49) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31737319 | 0.84 | LMNA (0.49) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31152283 | 0.84 | LMNA (0.49) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL31152318 | 0.83 | LMNA (0.51) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL31152251 | 0.83 | LMNA (0.51) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL31152303 | 0.83 | LMNA (0.51) | LMNAMAPTCYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049402-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |