Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1976599 | 0.95 | KDM4E (0.50) | KDM4ETP53BBOX1LMNAKMT2A | |
| SCHEMBL222638 | 0.92 | KDM4E (0.52) | KDM4ETP53BBOX1LMNAKMT2A | |
| Ammonia Solution, Strong SCHEMBL17998010 | 0.92 | KDM4E (0.46) | KDM4ETP53BBOX1LMNAKMT2A | |
| Bromide SCHEMBL2191358 | 0.92 | KDM4E (0.46) | KDM4ETP53BBOX1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL16931602 | 0.90 | KDM4E (0.50) | KDM4ETP53BBOX1LMNAKMT2A | |
| Fluoride Ion SCHEMBL1977758 | 0.90 | KDM4E (0.50) | KDM4ETP53BBOX1LMNAKMT2A | |
| Water SCHEMBL15375422 | 0.90 | KDM4E (0.50) | KDM4ETP53BBOX1LMNAKMT2A | |
| Iodide SCHEMBL16107572 | 0.90 | KDM4E (0.56) | KDM4ETP53BBOX1LMNAKMT2A | |
| SCHEMBL302222 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL715359 | 0.87 | BBOX1 (0.46) | KDM4ETP53BBOX1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025028579-A1 | METHOD FOR PRODUCING METATUNGSTATE COMPOUND, METATUNGSTATE COMPOUND FOR RESISTS, AND RESIST MATERIAL | 東京応化工業株式会社 | 2025-02-06 | — | — | WO | disclosed |