SCHEMBL31409201

SCHEMBL31409201

Nc1ccc(C(c2ccc(N)cc2)c2cccc(Cl)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
ALOX12 P18054 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
CYP19A1 P11511 4/20 0.40
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 1/20 0.40
ACP3 P15309 1/20 0.40
AOC3 Q16853 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
OPRM1 P35372 3/20 0.38
OPRD1 P41143 3/20 0.38
OPRK1 P41145 3/20 0.38
OPRL1 P41146 3/20 0.38
PNMT P11086 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22050359 0.85 MEN1 (0.40) ALDH1A1MAPTSMN1; SMN2GAACYP19A1
SCHEMBL4088685 0.85 ACP3 (0.48) ALDH1A1MGAMGAASIMGAM2
SCHEMBL20788381 0.81 ALDH1A1 (0.47) ALDH1A1LMNAMAPTALOX12SMN1; SMN2
SCHEMBL30529079 0.81 ALDH1A1 (0.47) ALDH1A1LMNAMAPTALOX12SMN1; SMN2
SCHEMBL7763010 0.80 ALDH1A1 (0.50) ALDH1A1CYP19A1
SCHEMBL1758048 0.80 TSHR (0.50) MGAMCYP19A1CYP11B1CYP11B2ACP3
SCHEMBL11376301 0.79 ALDH1A1 (0.45) ALDH1A1LMNAMAPTALOX12SMN1; SMN2
SCHEMBL5010075 0.78 CYP19A1 (0.56) ALDH1A1LMNAMAPTCYP19A1
SCHEMBL22051903 0.76 ACHE (0.48) ALDH1A1MAPTSMN1; SMN2MGAMGAA
SCHEMBL31409218 0.76 IDO1 (0.44) ALDH1A1MAPTSMN1; SMN2MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN claimed
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN disclosed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN disclosed