Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 7/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165650 | 0.92 | GRAMD1A (0.53) | GRAMD1AADORA1MKNK1MAPTKDM4E | |
| SCHEMBL31409422 | 0.86 | SCN4A (0.53) | GRAMD1AADORA1MAPTKDM4EGCK | |
| SCHEMBL741730 | 0.85 | ADORA1 (0.42) | GRAMD1AADORA1MKNK1MAPTKDM4E | |
| SCHEMBL19549675 | 0.84 | ADORA1 (0.48) | GRAMD1AADORA1MKNK1MAPTKDM4E | |
| SCHEMBL31409411 | 0.84 | GRAMD1A (0.45) | GRAMD1AADORA1MAPTKDM4EGCK | |
| SCHEMBL15282792 | 0.83 | GRAMD1A (0.44) | GRAMD1AADORA1MKNK1MAPTKDM4E | |
| SCHEMBL12761195 | 0.79 | GRAMD1A (0.53) | GRAMD1AADORA1MKNK1MAPTKDM4E | |
| SCHEMBL17993838 | 0.79 | GRAMD1A (0.53) | GRAMD1AADORA1MKNK1MAPTKDM4E | |
| SCHEMBL2699291 | 0.78 | GRAMD1A (0.53) | GRAMD1AADORA1MKNK1MAPTKDM4E | |
| SCHEMBL172106 | 0.78 | ADORA1 (0.56) | GRAMD1AADORA1MKNK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038920-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038917-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |