SCHEMBL172106

SCHEMBL172106

CC(C)(C)OC(=O)N1CCc2nc(N)sc2C1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.56
SCN4A P35499 1/20 0.53
GRAMD1A Q96CP6 1/20 0.53
SCN5A Q14524 1/20 0.50
SCN3A Q9NY46 1/20 0.50
MAPT P10636 3/20 0.48
KDM4E B2RXH2 1/20 0.48
RAD52 P43351 1/20 0.48
RECQL P46063 1/20 0.48
NR1H2 P55055 1/20 0.47
GCK P35557 6/20 0.43
ESR2 Q92731 1/20 0.42
PRKCI P41743 1/20 0.41
MKNK1 Q9BUB5 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31409422 0.92 SCN4A (0.53) ADORA1SCN4AGRAMD1ASCN5ASCN3A
SCHEMBL15001583 0.91 SCN4A (0.51) ADORA1SCN4AGRAMD1ASCN5ASCN3A
SCHEMBL17376986 0.90 ADORA1 (0.53) ADORA1SCN4AGRAMD1ASCN5ASCN3A
SCHEMBL741852 0.88 ADORA1 (0.47) ADORA1SCN4AGRAMD1ASCN5ASCN3A
SCHEMBL17993838 0.85 GRAMD1A (0.53) ADORA1GRAMD1AMAPTKDM4ENR1H2
SCHEMBL12761195 0.85 GRAMD1A (0.53) ADORA1GRAMD1AMAPTKDM4ENR1H2
SCHEMBL165650 0.85 GRAMD1A (0.53) ADORA1GRAMD1AMAPTKDM4ENR1H2
SCHEMBL17933982 0.85 RAD52 (0.51) ADORA1SCN4AGRAMD1ASCN5ASCN3A
SCHEMBL31143542 0.85 ADORA1 (0.51) ADORA1SCN4AGRAMD1AMAPTKDM4E
SCHEMBL2699291 0.84 GRAMD1A (0.53) ADORA1GRAMD1AMAPTKDM4ENR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138991-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS INC (US) 2026-05-21 US disclosed
EP-4705298-A2 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES Moma Therapeutics, Inc. (US) 2026-03-11 EP disclosed
US-12559508-B2 Semi-saturated bicyclic derivatives and related uses MOMA THERAPEUTICS, INC. (US) 2026-02-24 US disclosed
EP-4692057-A1 NOVEL B0AT1 INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2026-02-11 EP disclosed
US-20260001849-A1 NOVEL B0AT1 INHIBITOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-01-01 US disclosed
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
US-20250230171-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2025-07-17 US disclosed
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
US-20250066344-A1 BENZOTHIAZOLE, BENZOISOXAZOLE, AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-02-27 US disclosed
US-20240409533-A1 HMOX1 INDUCERS Astellas Engineered Small Molecules US, Incorporated 2024-12-12 US disclosed
WO-2006108709-A1 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2006-10-19 WO disclosed
US-20060223849-A1 Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors HIGH POINT PHARMACEUTICALS, LLC 2006-10-05 US disclosed
WO-2006099379-A2 BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS B-SECRETASE INHIBITORS TRANSTECH PHARMA, INC. (US) 2006-09-21 WO disclosed
US-20060004009-A1 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
EP-1577302-A1 NOVEL ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
EP-1562958-A1 N-SULFONYLAMINOTHIAZOLE Novartis AG (CH) 2005-08-17 EP disclosed
US-20040122063-A1 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-24 US disclosed
WO-2004043968-A1 N-SULFONYLAMINOTHIAZOLE NOVARTIS AG (CH) 2004-05-27 WO disclosed
EP-1270557-A1 ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001849-A1 NOVEL B0AT1 INHIBITOR BCAT1, BCAT2, BHMT ADORA1 1507/4885SCN4A 1857/4885GRAMD1A 3675/4885
US-20060004009-A1 Ethylenediamine derivatives F2, ECE1, MLLT1 ADORA1 1447/4885SCN4A 368/4885GRAMD1A 1049/4885
US-20250230171-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES POLQ, POLB, POLK ADORA1 2194/4885SCN4A 2873/4885GRAMD1A 2841/4885
US-20260138991-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES POLA1, SUB1, CTDSP1 ADORA1 192/4885SCN4A 1136/4885GRAMD1A 3607/4885
US-12559508-B2 Semi-saturated bicyclic derivatives and related uses POLA1, CTDSP1, SUB1 ADORA1 301/4885SCN4A 1310/4885GRAMD1A 2932/4885
US-20240409533-A1 HMOX1 INDUCERS HMOX1, HMOX2, HMBS ADORA1 1923/4885SCN4A 4427/4885GRAMD1A 4137/4885
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B ADORA1 113/4885SCN4A 56/4885GRAMD1A 4161/4885
US-20060223849-A1 Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors BACE1, BACE2, APP ADORA1 1923/4885SCN4A 2372/4885GRAMD1A 3545/4885
US-20250066344-A1 BENZOTHIAZOLE, BENZOISOXAZOLE, AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS RXFP1, RXFP2, RXFP3 ADORA1 602/4885SCN4A 3723/4885GRAMD1A 3105/4885
US-20040122063-A1 Ethylenediamine derivatives ECE1, F2, ECE2 ADORA1 1150/4885SCN4A 1233/4885GRAMD1A 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.