Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | PRF1 | P14222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499130 | 0.84 | GRM5 (0.46) | ADAM17PRMT5WDR77CRBNPRF1 | |
| SCHEMBL29438592 | 0.84 | PRMT5 (0.48) | PRMT5WDR77CYP2D6MAOAMAOB | |
| SCHEMBL471625 | 0.84 | PRMT5 (0.48) | PRMT5WDR77CYP2D6MAOAMAOB | |
| SCHEMBL22151770 | 0.83 | ADAM17 (0.48) | ADAM17PRMT5WDR77PRF1GRM5 | |
| SCHEMBL31409552 | 0.83 | ADAM17 (0.46) | ADAM17PRMT5WDR77CRBNMEN1 | |
| SCHEMBL6440457 | 0.82 | ADAM17 (0.47) | ADAM17PRMT5WDR77CRBNPRF1 | |
| SCHEMBL6071228 | 0.81 | PRMT5 (0.55) | ADAM17PRMT5WDR77MAOAMAOB | |
| SCHEMBL1026421 | 0.81 | GRM5 (0.44) | PRF1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL21481250 | 0.80 | HTR2A (0.46) | PRF1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL1029578 | 0.80 | HSD17B3 (0.49) | PRMT5WDR77PRF1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006553-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-01-02 | — | — | WO | disclosed |