Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | TFPI | P10646 | 1/20 | 0.38 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.38 |
| ▸ | NPY4R | P50391 | 4/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31410838 | 0.96 | TFPI (0.43) | KEAP1OPRL1TFPIIL23RNPY4R | |
| SCHEMBL31410656 | 0.90 | OPRL1 (0.41) | KEAP1OPRL1TFPINPY4RNPY1R | |
| SCHEMBL29536042 | 0.89 | GNPAT (0.44) | KEAP1OPRL1TFPIIL23RNPY4R | |
| SCHEMBL29375093 | 0.89 | TFPI (0.40) | KEAP1OPRL1TFPIIL23RNPY4R | |
| SCHEMBL31571454 | 0.89 | NPY4R (0.41) | KEAP1OPRL1NPY4RNPY1RNPY2R | |
| SCHEMBL30658141 | 0.88 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31410682 | 0.88 | NPY4R (0.46) | KEAP1TFPINPY4RNPY1RNPY2R | |
| SCHEMBL30471851 | 0.88 | PDCD1LG2 (0.39) | KEAP1OPRL1TFPIIL23R | |
| SCHEMBL30297059 | 0.88 | IL23R (0.42) | KEAP1OPRL1TFPIIL23RNPY4R | |
| SCHEMBL31410680 | 0.87 | NPY4R (0.45) | KEAP1OPRL1TFPIIL23RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462820-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Gly-Gly as well as preparation and application thereof | 首都医科大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-119390755-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Val-Val, preparation and application thereof | 首都医科大学 | 2025-02-07 | — | — | CN | disclosed |