Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | NPY4R | P50391 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.38 |
| ▸ | CALCR | P30988 | 3/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | TFPI | P10646 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031526 | 0.92 | RAMP3 (0.43) | RAMP3CALCRTFPI | |
| SCHEMBL31571454 | 0.91 | NPY4R (0.41) | OPRL1KEAP1NPY1RNPY2RNPY4R | |
| SCHEMBL31410686 | 0.90 | KEAP1 (0.41) | OPRL1KEAP1NPY1RNPY2RNPY4R | |
| SCHEMBL30903462 | 0.90 | NPY4R (0.46) | NPY1RNPY2RNPY4RNPY5RRAMP3 | |
| SCHEMBL30887059 | 0.89 | OPRL1 (0.42) | OPRL1KEAP1NPY1RNPY2RNPY4R | |
| SCHEMBL5849470 | 0.89 | OPRL1 (0.40) | OPRL1KEAP1NPY1RNPY2RNPY4R | |
| SCHEMBL14193566 | 0.89 | GNPAT (0.40) | OPRL1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29772973 | 0.89 | NOD1 (0.41) | KEAP1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL5849482 | 0.89 | OPRL1 (0.40) | OPRL1KEAP1NPY1RNPY2RNPY4R | |
| SCHEMBL29536066 | 0.89 | GNPAT (0.50) | OPRL1KEAP1NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462820-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Gly-Gly as well as preparation and application thereof | 首都医科大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-119390755-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Val-Val, preparation and application thereof | 首都医科大学 | 2025-02-07 | — | — | CN | disclosed |