Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906311 | 1.00 | DGAT1 (0.34) | DGAT1NPC1BRD4CREBBPMAPT | |
| SCHEMBL25240181 | 0.87 | DGAT1 (0.38) | DGAT1NPC1MAPT | |
| SCHEMBL30442967 | 0.87 | DGAT1 (0.38) | DGAT1NPC1MAPT | |
| SCHEMBL31343229 | 0.85 | DGAT1 (0.33) | DGAT1NPC1MAPT | |
| SCHEMBL22252732 | 0.85 | DGAT1 (0.33) | DGAT1NPC1MAPT | |
| SCHEMBL22252742 | 0.83 | DGAT1 (0.33) | DGAT1NPC1MAPT | |
| SCHEMBL31343232 | 0.83 | DGAT1 (0.33) | DGAT1NPC1MAPT | |
| SCHEMBL22252858 | 0.82 | NR4A2 (0.32) | DGAT1NPC1 | |
| SCHEMBL2279186 | 0.82 | DGAT1 (0.32) | DGAT1NPC1MAPT | |
| SCHEMBL31343370 | 0.82 | NR4A2 (0.32) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025014963-A1 | INHIBITORS OF P97 PROTEIN AND METHODS OF USE | GANDEEVA THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |