SCHEMBL3141099

SCHEMBL3141099

CCO[Si](CCCCC(C)N)(OCC)OCC

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.50
TP53 P04637 1/20 0.41
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28441728 0.98 OPRM1 (0.48) OPRM1TP53ALDH1A1TDP1
SCHEMBL28670104 0.93 OPRM1 (0.46) OPRM1TP53ALDH1A1TDP1
SCHEMBL22229596 0.87 OPRM1 (0.34) OPRM1ALDH1A1
SCHEMBL21723510 0.84 LMNA (0.39) OPRM1
SCHEMBL638552 0.84 OPRM1 (0.39) OPRM1TP53ALDH1A1
SCHEMBL28622632 0.83 OPRM1 (0.52) OPRM1TP53ALDH1A1TDP1
SCHEMBL23658241 0.83 LMNA (0.37) OPRM1
SCHEMBL27609334 0.83 LMNA (0.37) OPRM1
SCHEMBL147563 0.83 LMNA (0.37) OPRM1
SCHEMBL11176486 0.82 OPRM1 (0.31) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100078104-A1 Siloxane-based lubricating compositions that release no hydrogen BLUESTAR SILICONES FRANCE (FR) 2010-04-01 US disclosed
EP-2038354-A1 SILOXANE-BASED LUBRICATING COMPOSITION RELEASING NO HYDROGEN, ITS METHOD OF PREPARATION AND ITS USE Bluestar Silicones France (FR) 2009-03-25 EP disclosed
WO-2008000816-A1 METHOD FOR WATERPROOFING A SUBSTRATE BLUESTAR SILICONES FRANCE (FR) 2008-01-03 WO disclosed
WO-2007147787-A1 SILOXANE-BASED LUBRICATING COMPOSITION RELEASING NO HYDROGEN, ITS METHOD OF PREPARATION AND ITS USE BLUESTAR SILICONES FRANCE (FR) 2007-12-27 WO disclosed
US-6846780-B2 Siloxane-based lubricant composition, not releasing hydrogen, preparation method and use thereof RHODIA CHIMIE (FR) 2005-01-25 US disclosed
US-6825153-B2 OIL-IN-WATER EMULSION COMPRISING A POLYDIORGANOSILOXANE OIL NON-REACTIVE TO THE LUBRICATING PROPERTIES, A POLYORGANOSILOXANE RESIN, CROSSLINKING AGENT RHODIA CHIMIE (FR) 2004-11-30 US disclosed
EP-1240283-B1 LUBRICATING COMPOSITION BASED ON SILOXANE, NOT RELEASING HYDROGEN, PREPARATION METHOD AND USE THEREOF RHODIA CHIMIE SA (FR) 2004-03-17 EP disclosed
US-20030114321-A1 Lubricating composition based on siloxane, not releasing hydrogen , preparation method and use thereof BLUESTAR SILICONES FRANCE SAS (FR) 2003-06-19 US disclosed
US-20030109386-A1 Siloxane-based lubricant composition, not releasing hydrogen, preparation method and use thereof RHODIA CHIMIE (FR) 2003-06-12 US disclosed
EP-1250405-A1 SILOXANE-BASED LUBRICATING COMPOSITION, NOT RELEASING HYDROGEN, PREPARATION METHOD AND USE THEREOF RHODIA CHIMIE (FR) 2002-10-23 EP disclosed
EP-1240283-A1 LUBRICATING COMPOSITION BASED ON SILOXANE, NOT RELEASING HYDROGEN, PREPARATION METHOD AND USE THEREOF RHODIA CHIMIE (FR) 2002-09-18 EP disclosed
WO-2001044416-A1 SILOXANE-BASED LUBRICATING COMPOSITION, NOT RELEASING HYDROGEN, PREPARATION METHOD AND USE THEREOF RHODIA CHIMIE (FR) 2001-06-21 WO disclosed
WO-2001040417-A1 LUBRICATING COMPOSITION BASED ON SILOXANE, NOT RELEASING HYDROGEN, PREPARATION METHOD AND USE THEREOF RHODIA CHIMIE (FR) 2001-06-07 WO disclosed
EP-0311061-B1 COMPOSITION FOR THE SURFACE TREATMENT OF RUBBER TORAY SILICONE COMPANY, LIMITED (JP) 1993-02-24 EP disclosed
US-4889770-A POLYSILOXANE, SILANE COUPLING AGENT AND CATALYST TORAY SILICONE COMPANY LIMITED (JP) 1989-12-26 US disclosed
EP-0311061-A2 Composition for the surface treatment of rubber TORAY SILICONE COMPANY, LIMITED (JP) 1989-04-12 EP disclosed
US-4228054-A Organopolysiloxane latex compositions TORAY SILICONE COMPANY, LTD. (JP) 1980-10-14 US disclosed