SCHEMBL31411391

SCHEMBL31411391

COc1c(F)ccc2[nH]nc(CCN(C)C3CC3)c12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CHIA Q9BZP6 10/20 0.33
▸ CHIT1 Q13231 9/20 0.33
▸ HTR2A P28223 1/20 0.33
▸ MCHR1 Q99705 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.30
▸ CHI3L1 P36222 1/20 0.30
▸ CHI3L2 Q15782 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411367 0.85 HTR1A (0.40) HTR2A
SCHEMBL31411359 0.82 HTR2A (0.36) HTR2A
SCHEMBL31411330 0.81 HTR1A (0.30) HTR2A
SCHEMBL31411320 0.74 HTR1A (0.44) —
SCHEMBL31411348 0.73 SLC6A4 (0.42) HTR2A
SCHEMBL31411335 0.69 HTR2B (0.38) HTR2A
SCHEMBL31411452 0.68 HTR1A (0.59) HTR2A
SCHEMBL186075 0.67 KDR (0.42) —
SCHEMBL31411291 0.67 GRM4 (0.33) MCHR1
SCHEMBL31411322 0.66 HTR2A (0.39) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 — — EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 — — US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 — — US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 — — US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB CHIA 2913/4885CHIT1 3750/4885HTR2A 94/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB CHIA 2913/4885CHIT1 3750/4885HTR2A 94/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB CHIA 2913/4885CHIT1 3750/4885HTR2A 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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