Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | MPO | P05164 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952281 | 0.82 | AR (0.36) | CHEK1GPR84ARMPOSLC6A4 | |
| SCHEMBL786302 | 0.73 | CHEK1 (0.60) | CHEK1GPR84ARMPOSLC6A4 | |
| SCHEMBL30998058 | 0.72 | AR (0.38) | GPR84ARMPOSLC6A4MAPK10 | |
| SCHEMBL31539823 | 0.72 | CHEK1 (0.44) | CHEK1GPR84ARMPOSLC6A4 | |
| SCHEMBL4234184 | 0.72 | ADORA2A (0.41) | CHEK1GPR84ARMPOSLC6A4 | |
| SCHEMBL11903870 | 0.72 | GPR84 (0.39) | CHEK1GPR84ARMPOSLC6A4 | |
| SCHEMBL14158301 | 0.72 | CHEK1 (0.40) | CHEK1GPR84ARMPOSLC6A4 | |
| SCHEMBL14158228 | 0.72 | GPR84 (0.39) | CHEK1GPR84ARMPOSLC6A4 | |
| SCHEMBL31411346 | 0.71 | CHEK1 (0.39) | CHEK1GPR84FLT3MAPK10FEN1 | |
| SCHEMBL31190846 | 0.69 | KDM4E (0.52) | CHEK1FLT3MAPK10RIPK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735425-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2026-05-06 | — | — | EP | disclosed |
| US-20250353818-A1 | Compounds | Psylo Pty Ltd (AU) | 2025-11-20 | — | — | US | disclosed |
| US-12428380-B2 | Compounds | Psylo Pty Ltd (AU) | 2025-09-30 | — | — | US | disclosed |
| US-20250214943-A1 | Compounds | Psylo Pty Ltd (AU) | 2025-07-03 | — | — | US | disclosed |
| WO-2025000053-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2025-01-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214943-A1 | Compounds | NLN, SLC18A2, PYGB | CHEK1 2942/4885GPR84 3280/4885AR 3574/4885 |
| US-12428380-B2 | Compounds | NLN, SLC18A2, PYGB | CHEK1 2942/4885GPR84 3280/4885AR 3574/4885 |
| US-20250353818-A1 | Compounds | NLN, SLC18A2, PYGB | CHEK1 2942/4885GPR84 3280/4885AR 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.