Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411609 | 0.93 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBMAPTNPC1TP53 | |
| SCHEMBL31411572 | 0.88 | MAPT (0.48) | SMN1; SMN2POLBMAPTNPC1TP53 | |
| SCHEMBL31411693 | 0.81 | POLB (0.50) | SMN1; SMN2POLBMAPTNPC1GSK3B | |
| SCHEMBL31411673 | 0.81 | MAPT (0.53) | SMN1; SMN2POLBMAPTNPC1TP53 | |
| SCHEMBL31411598 | 0.81 | KCNN4 (0.41) | SMN1; SMN2POLBMAPTNPC1GSK3B | |
| SCHEMBL31411774 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2POLBMAPTNPC1GSK3B | |
| SCHEMBL31411784 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2POLBMAPTNPC1GSK3B | |
| SCHEMBL31411536 | 0.81 | GSK3B (0.56) | SMN1; SMN2POLBMAPTGSK3BTP53 | |
| SCHEMBL31411631 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2POLBMAPTALDH1A1LMNA | |
| SCHEMBL31411575 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBMAPTNPC1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |