Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411572 | 0.93 | MAPT (0.48) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411609 | 0.88 | SMN1; SMN2 (0.54) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411544 | 0.81 | SMN1; SMN2 (0.48) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL23768992 | 0.81 | ALDH1A1 (0.71) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29978848 | 0.81 | ALDH1A1 (0.71) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411689 | 0.81 | ALDH1A1 (0.56) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411794 | 0.80 | ALDH1A1 (0.39) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411600 | 0.79 | HPGD (0.61) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411587 | 0.78 | MAPT (0.67) | MAPTPOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411550 | 0.77 | LMNA (0.58) | MAPTPOLBALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |