Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411593 | 0.84 | DHPS (0.37) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31411636 | 0.82 | ALOX15 (0.42) | NPC1RAB9AMAPTMAPK1ALOX15 | |
| SCHEMBL31411527 | 0.82 | SNCA (0.35) | RAB9AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL31411822 | 0.77 | SIRT2 (0.39) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL31411853 | 0.76 | NPC1 (0.41) | NPC1RAB9AKDM4EHTTMAPT | |
| SCHEMBL31411701 | 0.76 | SMN1; SMN2 (0.38) | NPC1RAB9AKDM4EMAPTMAPK1 | |
| SCHEMBL31411670 | 0.75 | MAPT (0.43) | RAB9AHTTMAPTALDH1A1MEN1 | |
| SCHEMBL31411573 | 0.74 | CFTR (0.34) | MAPTPOLB | |
| SCHEMBL31411648 | 0.74 | MAPT (0.41) | NPC1MAPTSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL31411624 | 0.73 | DHPS (0.35) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |