Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720691 | 0.84 | NOTUM (0.54) | BPTFHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL21135447 | 0.81 | CYP2D6 (0.52) | NOTUMCYP2D6MAPT | |
| SCHEMBL6648521 | 0.81 | CYP2D6 (0.52) | NOTUMCYP2D6MAPT | |
| SCHEMBL21135739 | 0.81 | CYP2D6 (0.52) | NOTUMCYP2D6MAPT | |
| SCHEMBL987932 | 0.79 | MBTD1 (0.52) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL23983401 | 0.79 | MAPT (0.44) | ADRA2CLMNAGBA1MAPTNPSR1 | |
| SCHEMBL21135737 | 0.79 | NOTUM (0.45) | NOTUMDRD4LMNAMAPTNPSR1 | |
| SCHEMBL21877146 | 0.79 | LTA4H (0.40) | DRD4CYP2D6MGLLMAPT | |
| SCHEMBL23602982 | 0.79 | SLC6A2 (0.38) | DRD4MAPTNPSR1 | |
| SCHEMBL25141511 | 0.79 | USP2 (0.51) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |