SCHEMBL3141166

SCHEMBL3141166

O=[N+]([O-])C(=C([N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 3/20 0.33
HPGD P15428 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11792060 0.95 CA5A (0.46) CA5ACA5BMEN1KMT2AALDH1A1
SCHEMBL31339221 0.78
SCHEMBL10906198 0.78
SCHEMBL719016 0.76 CA5A (0.38) CA5ACA5BMEN1KMT2AALDH1A1
SCHEMBL6552272 0.76 CA5A (0.38) CA5ACA5BMEN1KMT2AALDH1A1
SCHEMBL3138751 0.70 CA5A (0.50) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL10981408 0.67
Nitric Acid SCHEMBL37356 0.67
Nitric Acid SCHEMBL234 0.67
Nitric Acid SCHEMBL3762342 0.67 CA5A (1.00) CA5ACA5BMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6835842-B2 Microbiocides; bactericides BAYER AKTIENGESELLSCHAFT (DE) 2004-12-28 US claimed
US-20030207929-A1 3-nitroisoxazoles and their use in the protection of materials LANXESS DEUTSCHLAND GMBH (DE) 2003-11-06 US claimed
US-20030166698-A1 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2003-09-04 US claimed
EP-1335909-A1 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS Bayer Aktiengesellschaft (DE) 2003-08-20 EP claimed
WO-2002034731-A1 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 2002-05-02 WO claimed
US-7641748-B2 Highly energy-producing compound DIEHL BGT DEFENCE GMBH & CO., KG (DE) 2010-01-05 US disclosed
US-20090299106-A1 HIGHLY ENERGY-PRODUCING COMPOUND DIEHL BGT DEFENCE GMBH & CO., KG (DE) 2009-12-03 US disclosed
EP-1767519-A1 Highly energised compounds Diehl BGT Defence GmbH & Co.KG (DE) 2007-03-28 EP disclosed
US-6835842-B2 Microbiocides; bactericides BAYER AKTIENGESELLSCHAFT (DE) 2004-12-28 US disclosed
US-20030207929-A1 3-nitroisoxazoles and their use in the protection of materials LANXESS DEUTSCHLAND GMBH (DE) 2003-11-06 US disclosed
US-6638958-B2 3-nitroisoxazoles and their use in the protection of materials BAYER AKTIENGESELLSCHAFT (DE) 2003-10-28 US disclosed
US-20030166698-A1 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS LANXESS DEUTSCHLAND GMBH (DE) 2003-09-04 US disclosed
EP-1335909-A1 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS Bayer Aktiengesellschaft (DE) 2003-08-20 EP disclosed
WO-2002042282-A1 METHOD FOR PRODUCING NITRO-DIHYDROISOXAZOLES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-30 WO disclosed
WO-2002034731-A1 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 2002-05-02 WO disclosed
WO-2001046163-A2 3-NITRO-DIHYDRO-ISOXAZOLES AND OXAZINES AND THEIR USE AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-06-28 WO disclosed
US-5332820-A Diuretic, hypotensive agent, treating congestive heart failure E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166698-A1 3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS GPX1, NOX1, XDH CA5A 632/4885CA5B 977/4885MEN1 1505/4885
US-20030207929-A1 3-nitroisoxazoles and their use in the protection of materials GPX1, NOX1, XDH CA5A 632/4885CA5B 977/4885MEN1 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.