SCHEMBL31411684

SCHEMBL31411684

CC1(C)C(=O)N(Cc2ccn(-c3ccccc3)c2)c2cc(C(=O)Nc3c[nH]c4ccccc34)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPT1A P50416 2/20 0.40
CPT1B Q92523 2/20 0.40
CPT2 P23786 1/20 0.40
TP53 P04637 4/20 0.38
MAPT P10636 4/20 0.38
STING1 Q86WV6 5/20 0.37
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ROCK2 O75116 1/20 0.33
GRK2 P25098 1/20 0.33
HDAC1 Q13547 2/20 0.33
RAB9A P51151 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
CFTR P13569 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411832 0.91 CPT1A (0.35) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411617 0.89 TP53 (0.48) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411749 0.83 CPT1A (0.39) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411552 0.82 CA12 (0.42) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411560 0.82 CFTR (0.42) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411588 0.82 CPT1A (0.42) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411721 0.81 CPT1A (0.44) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411761 0.80 ALDH1A1 (0.40) CPT1ACPT1BCPT2TP53MAPT
SCHEMBL31411901 0.80 MAPT (0.46) CPT1ACPT1BCPT2MAPTSTING1
SCHEMBL31411710 0.79 CRHR1 (0.45) CPT1ACPT1BCPT2STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330982-A Azetidine compound and medical application thereof 中国科学院上海药物研究所 2025-01-21 CN disclosed