Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411750 | 0.86 | STING1 (0.42) | SIRT2MAPTLMNAGSK3AGSK3B | |
| SCHEMBL31411822 | 0.85 | SIRT2 (0.39) | SIRT2MAPTLMNAGSK3AGSK3B | |
| SCHEMBL31411674 | 0.82 | MAPT (0.50) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL31411677 | 0.82 | MAPT (0.57) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL31411650 | 0.78 | GSK3A (0.54) | MAPTLMNAGSK3AGSK3BSMN1; SMN2 | |
| SCHEMBL25138317 | 0.78 | STING1 (0.49) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL30882832 | 0.78 | STING1 (0.49) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL29979063 | 0.78 | STING1 (0.49) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL25037393 | 0.78 | STING1 (0.49) | MAPTLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL31411624 | 0.77 | DHPS (0.35) | DHPSSTING1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |