Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411669 | 0.89 | SMN1; SMN2 (0.48) | GSK3AGSK3BALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411751 | 0.84 | GSK3A (0.45) | GSK3AGSK3BALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6993171 | 0.80 | GSK3A (0.54) | GSK3AGSK3BALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL31411697 | 0.78 | SIRT2 (0.39) | GSK3AGSK3BALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL23768992 | 0.74 | ALDH1A1 (0.71) | ALDH1A1CYP2C9CYP2C19MAPTPOLB | |
| SCHEMBL29978848 | 0.74 | ALDH1A1 (0.71) | ALDH1A1CYP2C9CYP2C19MAPTPOLB | |
| SCHEMBL21972975 | 0.72 | ALDH1A1 (0.64) | GSK3BALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL29978554 | 0.72 | ALDH1A1 (0.64) | GSK3BALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL31411536 | 0.72 | GSK3B (0.56) | GSK3AGSK3BALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7366310 | 0.72 | TSHR (0.78) | GSK3AGSK3BALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |