SCHEMBL3141201

SCHEMBL3141201

CCCCn1c(S)nc2ccc3ccccc3c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.45
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PDE10A Q9Y233 1/20 0.41
SIRT2 Q8IXJ6 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
PGR P06401 1/20 0.39
RORA P35398 1/20 0.39
RORC P51449 1/20 0.39
RORB Q92753 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
PTK2B Q14289 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PIM3 Q86V86 1/20 0.37
GAA P10253 1/20 0.37
MPO P05164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16512991 0.79 TLR8 (0.64) TLR8
SCHEMBL10739963 0.75 ALDH1A1 (0.60) TDP1L3MBTL1PGRRORARORC
SCHEMBL3840545 0.74 TLR8 (0.67) TLR8L3MBTL1TSHRSMN1; SMN2ALDH1A1
SCHEMBL10477211 0.72 PGR (0.56) TLR8TDP1L3MBTL1PGRRORA
SCHEMBL3137088 0.70 TLR8 (0.68) TLR8TDP1TSHRSMN1; SMN2ALDH1A1
SCHEMBL14141845 0.70 TDP1 (0.69) TDP1L3MBTL1SIRT2SIRT1PGR
SCHEMBL31265546 0.69 TLR8 (0.55) TLR8TDP1L3MBTL1SIRT2SIRT1
SCHEMBL3136462 0.69 TLR8 (0.68) TLR8TDP1TSHRSMN1; SMN2ALDH1A1
SCHEMBL15382597 0.69 TLR8 (0.68) TLR8TDP1TSHRSMN1; SMN2ALDH1A1
SCHEMBL3141446 0.69 TLR8 (0.68) TLR8TDP1TSHRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 EP disclosed